产品货号:
Z10405
中文名称:
ACVR1抗体
英文名称:
Anti-ACVR1 Antibody(Center R147)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACVR1 Antibody (Center R147) |
指标别名 | activin A receptor;type I;Activin receptor like kinase 2;Activin receptor type 1;Activin receptor type I;ACTR I;ACTRI;ACVR1;ACVR1A;ACVRLK2;ALK 2;ALK2;FOP;SKR1;TSR I;TSRI |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC |
基因名称 | ACVR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This Activin Receptor Type IA (ACVR1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-162 amino acids from the Central region of human Activin Receptor Type IA (ACVR1). |
计算分子量 | 57kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins,composed of a ligand-binding extracellular domain with cysteine-rich region,a transmembrane domain,and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling;and type II receptors are required for binding ligands and for expression of type I receptors.Type I and II receptors form a stable complex after ligand binding,resulting in phosphorylation of type I receptors by type II receptors.ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors. |
Uniprot ID | Q04771 |
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